The RhoB Monoclonal Antibody is a key tool for researchers studying the RhoB protein, which plays a crucial role in cellular processes such as cell migration, proliferation, and apoptosis. This antibody, produced through monoclonal antibody technology, is highly specific to RhoB and shows minimal cross-reactivity with other proteins, ensuring reliable and accurate results in experiments.With its ability to recognize and bind specifically to the RhoB protein, this antibody is ideal for applications such as Western blotting, immunofluorescence, and immunohistochemistry. By enabling the detection and visualization of RhoB in various cell types and tissues, researchers can gain valuable insights into the function and regulation of this important signaling molecule.
The RhoB Monoclonal Antibody is a valuable tool for investigations in areas such as cancer research, where dysregulation of RhoB signaling pathways has been implicated in tumor development and progression. By studying the expression and localization of RhoB using this antibody, researchers can deepen their understanding of the mechanisms underlying cancer biology and potentially identify new therapeutic targets for intervention.
Product Name:
RhoB Monoclonal Antibody
SKU:
CAB22258
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human RhoB (NP_004031.1).
Cell membrane, Cleavage furrow, Late endosome membrane, Lipid-anchor, Nucleus.
Calculated MW:
22kDa
Observed MW:
22kDa
Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Involved in several processes, including cellular response to hydrogen peroxide; cellular response to ionizing radiation; and regulation of cell migration. Located in cleavage furrow and endosome membrane. Biomarker of breast cancer.
Purification Method:
Affinity purification
Gene ID:
388
Clone Number:
ARC56483
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using RhoB antibody (CAB22258) at1:20000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
