RHOA/RHOB/RHOC Rabbit Monoclonal Antibody (CAB4855)
- SKU:
- CAB4855
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ARH9
- ARHC
- H9
- RHOH9
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | RHOA/RHOB/RHOC Rabbit Monoclonal Antibody |
SKU: | CAB4855 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human RHOA/RHOB/RHOC (P08134). |
Sequence: | MAAI RKKL VIVG DGAC GKTC LLIV FSKD QFPE VYVP TVFE NYIA DIEV DGKQ VELA LWDT AGQE DYDR LRPL SYPD TDVI LMCF SIDS PDSL ENIP EKWT PEVK HFCP NVPI ILVG NKKD LRQD EHTR RELA KMKQ EPVR SEEG RDMA NRIS AFGY LECS AKTK EGVR EVFE MATR AGLQ VRKN KRRR GCPI L |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ARH9; ARHC; H9; RHOH9; RHOA/RHOB/RHOC |
Positive Sample: | HeLa,MCF7,NIH/3T3,SH-SY5Y,HUVEC,Mouse brain,Mouse kidney,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cell cortex, cell projection, cytoplasmic vesicle, cytoskeleton, cytosol, extracellular exosome, neuron projection, nucleus, plasma membrane |
Calculated MW: | 22kDa |
Observed MW: | 22kDa |
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Purification Method: | Affinity purification |
Gene ID: | 389/387/388 |
Clone Number: | ARC0273 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |