[KO Validated] RhoA Rabbit Polyclonal Antibody (CAB15641)
- SKU:
- CAB15641
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | [KO Validated] RhoA Rabbit Polyclonal Antibody |
SKU: | CAB15641 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human RhoA (NP_001655.1). |
Sequence: | MAAI RKKL VIVG DGAC GKTC LLIV FSKD QFPE VYVP TVFE NYVA DIEV DGKQ VELA LWDT AGQE DYDR LRPL SYPD TDVI LMCF SIDS PDSL ENIP EKWT PEVK HFCP NVPI ILVG NKKD LRND EHTR RELA KMKQ EPVK PEEG RDMA NRIG AFGY MECS AKTK DGVR EVFE MATR AALQ ARRG KKKS GCLV L |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | ARHA; ARH12; RHO12; EDFAOB; RHOH12; oA |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Cleavage furrow, Cytoplasm, Cytoplasmic side, Lipid-anchor, Midbody, cell cortex, cytoskeleton, lamellipodium. |
Calculated MW: | 22kDa |
Observed MW: | 21kDa |
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
Purification Method: | Affinity purification |
Gene ID: | 387 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |