RhoA Rabbit Polyclonal Antibody (CAB13947)
- SKU:
- CAB13947
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | RhoA Rabbit Polyclonal Antibody |
SKU: | CAB13947 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 94-193 of human RhoA (NP_001655.1). |
Sequence: | NIPE KWTP EVKH FCPN VPII LVGN KKDL RNDE HTRR ELAK MKQE PVKP EEGR DMAN RIGA FGYM ECSA KTKD GVRE VFEM ATRA ALQA RRGK KKSG CLVL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | ARHA; ARH12; RHO12; EDFAOB; RHOH12; RhoA |
Positive Sample: | NIH/3T3, Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Cleavage furrow, Cytoplasm, Cytoplasmic side, Lipid-anchor, Midbody, cell cortex, cytoskeleton, lamellipodium. |
Calculated MW: | 22kDa |
Observed MW: | 21kDa |
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
Purification Method: | Affinity purification |
Gene ID: | 387 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |