The Rho Antibody (PACO33720) is a polyclonal antibody specifically designed for research involving the Rho protein, a key regulator of cell shape, movement, and organization. The antibody, produced in rabbits, exhibits high reactivity with samples from various species and is validated for use in applications such as Western blotting and immunofluorescence.Rho is a member of the Ras superfamily of small GTPases and plays a crucial role in various cellular processes, including cell migration, adhesion, and cytokinesis. Dysregulation of Rho signaling has been implicated in diseases such as cancer, cardiovascular disorders, and neurodegenerative conditions, making it a significant target for therapeutic interventions.
By targeting the Rho protein, researchers can gain insights into the mechanisms underlying these diseases and develop novel treatments that specifically inhibit or enhance Rho signaling pathways. The Rho Antibody (PACO33720) is a valuable tool for investigating the functions and dysregulation of Rho in different cellular contexts, advancing our understanding of its role in health and disease.
Antibody Name:
rho Antibody (PACO33720)
Antibody SKU:
PACO33720
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Escherichia coli
Immunogen:
Recombinant Escherichia coli Transcription termination factor Rho protein (1-419AA)
Facilitates transcription termination by a mechanism that involves rho binding to the nascent RNA, activation of rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPAse which utilizes all four ribonucleoside triphosphates as substrates.
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPase which utilizes all four ribonucleoside triphosphates as substrates.
UniProt Protein Details:
NCBI Summary:
rho has been shown to be an essential gene (Das, 1976; Bubunenko, 2007). [More information is available at EcoGene: EG10845]. Rho is required for one of the two major types of termination of RNA transcription. [More information is available at EcoCyc: EG10845].
