The Rho Antibody (PACO33716) is a polyclonal antibody specifically designed for research involving Rho, a small GTPase protein that plays a key role in cellular processes such as cell migration, adhesion, and apoptosis. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications.Rho is a critical regulator of actin cytoskeleton dynamics, affecting various cellular functions such as cell shape, motility, and division. Dysregulation of Rho signaling has been implicated in a wide range of diseases, including cancer, cardiovascular disorders, and neurological conditions.
The Rho Antibody enables the detection and analysis of Rho protein levels in different cell types, making it an ideal tool for studying the role of Rho in cellular processes and disease pathogenesis. Its specificity and sensitivity make it a valuable asset for researchers in the fields of cell biology, oncology, and neuroscience. By understanding the mechanisms underlying Rho function, researchers can potentially develop targeted therapies for diseases associated with Rho dysregulation.
Antibody Name:
rho Antibody (PACO33716)
Antibody SKU:
PACO33716
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Escherichia coli
Immunogen:
Recombinant Escherichia coli Transcription termination factor Rho protein (1-419AA)
Facilitates transcription termination by a mechanism that involves rho binding to the nascent RNA, activation of rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPAse which utilizes all four ribonucleoside triphosphates as substrates.
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPase which utilizes all four ribonucleoside triphosphates as substrates.
UniProt Protein Details:
NCBI Summary:
rho has been shown to be an essential gene (Das, 1976; Bubunenko, 2007). [More information is available at EcoGene: EG10845]. Rho is required for one of the two major types of termination of RNA transcription. [More information is available at EcoCyc: EG10845].
