RheB Rabbit Polyclonal Antibody (CAB1165)
- SKU:
- CAB1165
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | RheB Rabbit Polyclonal Antibody |
SKU: | CAB1165 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human RheB (NP_005605.1). |
Sequence: | MPQS KSRK IAIL GYRS VGKS SLTI QFVE GQFV DSYD PTIE NTFT KLIT VNGQ EYHL QLVD TAGQ DEYS IFPQ TYSI DING YILV YSVT SIKS FEVI KVIH GKLL DMVG KVQI PIML VGNK KDLH MERV ISYE EGKA LAES WNAA FLES SAKE NQTA VDVF RRII LEAE KMDG AASQ GKSS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | RHEB2; RheB |
Positive Sample: | DU145,U-87MG,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic side, Endomembrane system, Endoplasmic reticulum membrane, Golgi apparatus membrane, Lipid-anchor, cytosol. |
Calculated MW: | 20kDa |
Observed MW: | 17kDa |
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Purification Method: | Affinity purification |
Gene ID: | 6009 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |