RGS4 Rabbit Polyclonal Antibody (CAB1787)
- SKU:
- CAB1787
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | RGS4 Rabbit Polyclonal Antibody |
SKU: | CAB1787 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RGS4 (NP_005604.1). |
Sequence: | MCKG LAGL PASC LRSA KDMK HRLG FLLQ KSDS CEHN SSHN KKDK VVIC QRVS QEEV KKWA ESLE NLIS HECG LAAF KAFL KSEY SEEN IDFW ISCE EYKK |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | RGP4; SCZD9; RGS4 |
Positive Sample: | U-251MG,HeLa,A-375,Jurkat,Raji |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, nucleus, plasma membrane |
Calculated MW: | 23kDa |
Observed MW: | 30kDa |
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5999 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |