The RGS13 Polyclonal Antibody (CAB10035) is a valuable tool for researchers studying the regulatory protein RGS13. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the RGS13 protein, this antibody allows for the detection and analysis of RGS13 in various cell types, making it ideal for studies in immunology and cancer research.RGS13, also known as Regulator of G protein Signaling 13, plays a crucial role in regulating G protein-coupled receptor signaling pathways, which are involved in a variety of cellular processes including immune response and cell proliferation.
Understanding the function of RGS13 is essential for unraveling the complexities of these pathways and developing targeted therapies for diseases such as cancer, autoimmune disorders, and inflammatory conditions.Overall, the RGS13 Polyclonal Antibody is a valuable tool for researchers looking to further their understanding of RGS13 and its role in cellular signaling pathways, making it a valuable asset in the field of biomedical research.
Product Name:
RGS13 Rabbit Polyclonal Antibody
SKU:
CAB10035
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-159 of human RGS13 (NP_002918.1).
The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist.
Purification Method:
Affinity purification
Gene ID:
6003
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RGS13 antibody (CAB10035) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
