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RGS12 Antibody (PACO20337)

SKU:
PACO20337
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339

Description

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RGS12 Antibody (PACO20337)

The RGS12 Polyclonal Antibody (PACO20337) offered by AssayGenie is a research tool designed for studying RGS12, a protein involved in cellular signaling pathways. This antibody is produced in rabbits and is highly specific for human samples, making it ideal for use in Western blot applications.RGS12 is a regulator of G protein signaling that plays a key role in modulating various cellular processes, including cell growth, differentiation, and migration. By targeting RGS12 with this antibody, researchers can effectively analyze its expression and function in different cell types, providing valuable insights into its involvement in diseases such as cancer and neurological disorders.

With its high reactivity and specificity, the RGS12 Polyclonal Antibody is a reliable tool for scientists conducting research in the fields of biochemistry, cell biology, and pharmacology. By enabling the precise detection and analysis of RGS12 protein levels, this antibody contributes to a better understanding of the molecular mechanisms underlying cellular signaling pathways and disease development.

Antibody Name:RGS12 Antibody (PACO20337)
Antibody SKU:PACO20337
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:Human
Immunogen:Synthetic peptide of human RGS12
Form:Liquid
Storage Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:Antigen affinity purification
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageGel: 6%SDS-PAGE, Lysate: 40 µg, Lane: Hela cells, Primary antibody: PACO20337(RGS12 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes.
Background:This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined.
Synonyms:regulator of G-protein signaling 12
UniProt Protein Function:RGS12: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. 4 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, misc.; GAPsChromosomal Location of Human Ortholog: 4p16.3Cellular Component: nuclear matrix; condensed nuclear chromosome; cytoplasm; nucleolus; plasma membrane; nucleusMolecular Function: receptor signaling protein activity; GTPase regulator activity; GTPase activator activityBiological Process: transcription, DNA-dependent; regulation of catalytic activity; regulation of G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity
UniProt Protein Details:
NCBI Summary:This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq]
UniProt Code:O14924
NCBI GenInfo Identifier:38327601
NCBI Gene ID:6002
NCBI Accession:NP_937872.1
UniProt Secondary Accession:O14924,O14922, O14923, O43510, O75338, B1AQ30, B1AQ31 B1AQ32
UniProt Related Accession:O14924, Q147X0, Q3B858, Q506M0, Q56A82, Q69YN1, Q8WX95, Q8WX96, Q8WX97
Molecular Weight:156,357 Da
NCBI Full Name:regulator of G-protein signaling 12 isoform 1
NCBI Synonym Full Names:regulator of G-protein signaling 12
NCBI Official Symbol:RGS12  
NCBI Official Synonym Symbols:DKFZp761K1617; DKFZp761K1817  
NCBI Protein Information:regulator of G-protein signaling 12; OTTHUMP00000115311; OTTHUMP00000115312; OTTHUMP00000151172; regulator of G-protein signalling 12
UniProt Protein Name:Regulator of G-protein signaling 12
UniProt Synonym Protein Names:
Protein Family:Regulator of G-protein signaling
UniProt Gene Name:RGS12  
UniProt Entry Name:RGS12_HUMAN
AntibodiesELISA Kits
RGS12 Antibody (PACO03065)Human RGS12 (Regulator of G-protein signaling 12) ELISA Kit (HUFI03391)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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