RGS10 Rabbit Polyclonal Antibody (CAB9948)
- SKU:
- CAB9948
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | RGS10 Rabbit Polyclonal Antibody |
SKU: | CAB9948 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human RGS10 (NP_001005339.1). |
Sequence: | MFNR AVSR LSRK RPPS DIHD SDGS SSSS HQSL KSTA KWAA SLEN LLED PEGV KRFR EFLK KEFS EENV LFWL ACED FKKM QDKT QMQE KAKE IYMT FLSS KASS QVNV EGQS RLNE KILE EPHP LMFQ KLQD QIFN LMKY DSYS RFLK SDLF LKHK RTEE EEED LPDA QTAA KRAS RIYN T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RGS10 |
Positive Sample: | HeLa,HepG2,HT-1080,Jurkat,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, nucleus, plasma membrane, synapse |
Calculated MW: | 21kDa |
Observed MW: | 20kDa |
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6001 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |