RGR Rabbit Polyclonal Antibody (CAB7925)
- SKU:
- CAB7925
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | RGR Rabbit Polyclonal Antibody |
SKU: | CAB7925 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 156-295 of human RGR (NP_002912.2). |
Sequence: | HYDY EPLG TCCT LDYS KGDR NFTS FLFT MSFF NFAM PLFI TITS YSLM EQKL GKSG HLQV NTTL PART LLLG WGPY AILY LYAV IADV TSIS PKLQ MVPA LIAK MVPT INAI NYAL GNEM VCRG IWQC LSPQ KREK DRTK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RP44; RGR |
Positive Sample: | rat spinal cord |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 32kDa |
Observed MW: | 32kDa |
This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 5995 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |