The RGP1 Polyclonal Antibody (PAC038658) is a valuable tool for research involving RGP1, a cell surface protein with potential implications in cancer biology and immune modulation. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. It binds to the RGP1 protein, allowing for accurate detection and analysis in various cell types, making it an ideal choice for studies in oncology and immunology.RGP1, also known as a potential regulator of immune responses, is a key player in the intricate network of pathways involved in cancer progression and immune system modulation.
Its role in regulating inflammation and potentially influencing tumor growth highlights its importance as a target for further research into cancer therapies and immunotherapies. Understanding the function of RGP1 is crucial for uncovering new treatment strategies for cancer and immune-related disorders.
Antibody Name:
RGP1 Antibody (PACO38658)
Antibody SKU:
PACO38658
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human RAB6A-GEF complex partner protein 2 protein (56-350AA)
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors.
Synonyms:
RAB6A-GEF complex partner protein 2 (Retrograde Golgi transport protein RGP1 homolog), RGP1, KIAA0258
UniProt Protein Function:
RGP1: Belongs to the RGP1 family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 9p13.3Cellular Component: cytosol; membrane; protein complex; trans-Golgi network membraneMolecular Function: protein binding; Rab GTPase binding; Rab guanyl-nucleotide exchange factor activityBiological Process: positive regulation of GTPase activity; retrograde transport, endosome to Golgi