The RGMB Polyclonal Antibody (CAB12859) is a valuable tool for researchers studying the RGMB protein, a cell surface molecule with important roles in neuronal development and regeneration. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the RGMB protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for studies in neuroscience and neurology research.RGMB, also known as repulsive guidance molecule B, plays a crucial role in axon guidance and synaptic plasticity, making it a key player in neural development and repair processes.
Understanding the functions of RGMB is essential for unraveling the mechanisms underlying neurodevelopmental disorders, neurodegenerative diseases, and brain injuries. The RGMB Polyclonal Antibody provides researchers with a reliable tool to investigate the expression and function of RGMB in various experimental contexts, ultimately advancing our knowledge of the nervous system and potentially leading to the development of therapeutic interventions for neurological conditions.
Product Name:
RGMB Rabbit Polyclonal Antibody
SKU:
CAB12859
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 210-453 of human RGMB (NP_001012779.2).
RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]).
Purification Method:
Affinity purification
Gene ID:
285704
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RGMB Rabbit pAb (CAB12859) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
