The RFX3 Polyclonal Antibody (CAB15311) is a powerful tool for researchers studying the RFX3 protein, a transcription factor crucial for the regulation of genes involved in immune responses and cell proliferation. This antibody, produced through rabbit immunization, exhibits high specificity and sensitivity for human samples, making it ideal for applications such as Western blotting.RFX3 plays a key role in the immune system by controlling the expression of genes that are essential for immune cell development and function. Dysregulation of RFX3 has been linked to autoimmune diseases, cancer, and other inflammatory conditions, highlighting its importance in immune system homeostasis.
By using the RFX3 Polyclonal Antibody, researchers can accurately detect and analyze RFX3 protein levels in different cell types, providing valuable insights into the mechanisms underlying immune-related diseases. This antibody is a valuable tool for immunology and cancer research, offering a deeper understanding of how RFX3 influences immune responses and potential therapeutic strategies for targeting this pathway.
Product Name:
RFX3 Rabbit Polyclonal Antibody
SKU:
CAB15311
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 280-430 of human RFX3 (NP_602304.1).
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
5991
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RFX3 Rabbit pAb (CAB15311) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
