RFC5 Rabbit Polyclonal Antibody (CAB8056)
- SKU:
- CAB8056
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RFC5 Rabbit Polyclonal Antibody |
SKU: | CAB8056 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 181-340 of human RFC5 (NP_031396.1). |
Sequence: | LMVP RLEH VVEE EKVD ISED GMKA LVTL SSGD MRRA LNIL QSTN MAFG KVTE ETVY TCTG HPLK SDIA NILD WMLN QDFT TAYR NITE LKTL KGLA LHDI LTEI HLFV HRVD FPSS VRIH LLTK MADI EYRL SVGT NEKI QLSS LIAA FQVT RDLI VAEA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RFC36; RFC5 |
Positive Sample: | HeLa,U-251MG,SKOV3,MCF-7,Mouse liver,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 38kDa |
Observed MW: | 38kDa |
This gene encodes the smallest subunit of the replication factor C complex, which consists of five distinct subunits (140, 40, 38, 37, and 36 kDa) and is required for DNA replication. This subunit interacts with the C-terminal region of proliferating cell nuclear antigen and is required to open and load proliferating cell nuclear antigen onto DNA during S phase. It is a member of the AAA+ (ATPases associated with various cellular activities) ATPase family and forms a core complex with the 38 and 40 kDa subunits that possesses DNA-dependent ATPase activity. A related pseudogene has been identified on chromosome 9. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5985 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |