RFC4 Rabbit Polyclonal Antibody (CAB5485)
- SKU:
- CAB5485
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RFC4 Rabbit Polyclonal Antibody |
SKU: | CAB5485 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 204-363 of human RFC4 (NP_002907.1). |
Sequence: | DKIQ QQRL LDIA KKEN VKIS DEGI AYLV KVSE GDLR KAIT FLQS ATRL TGGK EITE KVIT DIAG VIPA EKID GVFA ACQS GSFD KLEA VVKD LIDE GHAA TQLV NQLH DVVV ENNL SDKQ KSII TEKL AEVD KCLA DGAD EHLQ LISL CATV MQQL SQNC |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | A1; RFC37; RFC4 |
Positive Sample: | HeLa,SW480,22Rv1,SW620,K-562,HepG2,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 40kDa |
Observed MW: | 40kDa |
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
Purification Method: | Affinity purification |
Gene ID: | 5984 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |