The REXO2 Polyclonal Antibody (CAB15808) is a vital tool for researchers studying REXO2, a protein involved in DNA replication and repair processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the REXO2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for investigations in molecular biology and cancer research.REXO2 is known for its role in maintaining genomic stability and integrity by participating in key cellular processes such as DNA metabolism and nucleic acid processing.
Its involvement in DNA repair mechanisms suggests potential implications in diseases like cancer, where DNA damage repair pathways are often dysregulated. By utilizing the REXO2 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of REXO2, paving the way for advancements in understanding the molecular basis of cancer and potential therapeutic interventions.
Product Name:
REXO2 Rabbit Polyclonal Antibody
SKU:
CAB15808
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-237 of human REXO2 (NP_056338.2).
This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process.
Purification Method:
Affinity purification
Gene ID:
25996
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using REXO2 Rabbit pAb (CAB15808) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
