The REXO1 Monoclonal Antibody (PAC022582) is a valuable tool for researchers studying REXO1, a protein involved in DNA repair and replication processes. This antibody, produced in mice, has high specificity for human samples and has been validated for use in Western blot and immunohistochemistry applications. By targeting the REXO1 protein, this antibody allows for the detection and analysis of REXO1 expression in various cell types, making it ideal for studies in genetics, cancer research, and DNA damage response pathways.
REXO1 is a key player in maintaining genome integrity and stability by participating in DNA metabolism and repair mechanisms. Its role in DNA replication and genomic maintenance underscores its importance in understanding mechanisms of cancer development, genetic disorders, and cellular responses to DNA damage. By studying the function of REXO1, researchers can gain insights into potential therapeutic strategies targeting DNA repair pathways in diseases related to genomic instability.
Antibody Name:
REXO1 Antibody (PACO22582)
Antibody SKU:
PACO22582
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human REXO1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemistry analysis of paraffin-embedded human brain tissue using REXO1 antibody.
Background:
Seems to have no detectable effect on transcription elongation in vitro.
Synonyms:
EC 3.1.-.-; Elongin A-binding protein 1; EloA-BP1; Transcription elongation factor B polypeptide 3-binding protein 1;
UniProt Protein Function:
REXO1: Seems to have no detectable effect on transcription elongation in vitro. Belongs to the REXO1/REXO3 family.Protein type: Hydrolase; EC 3.1.-.-Chromosomal Location of Human Ortholog: 19p13.3Cellular Component: nucleoplasmMolecular Function: nucleic acid binding; exonuclease activity
