The REV-ERB BETA (NR1D2) Monoclonal Antibody is a highly specific and sensitive tool for researchers studying the REV-ERB BETA gene, which plays a key role in the regulation of circadian rhythm and metabolism. This antibody, produced using hybridoma technology, is validated for use in immunofluorescence, immunoprecipitation, and immunohistochemistry applications.The REV-ERB BETA protein is a nuclear receptor that functions as a transcriptional repressor, influencing the expression of genes involved in a variety of physiological processes, including metabolism, inflammation, and cell proliferation.
Dysregulation of REV-ERB BETA has been linked to metabolic disorders, cardiovascular disease, and cancer, making it a promising target for therapeutic interventions.This monoclonal antibody provides researchers with a valuable tool for investigating the role of REV-ERB BETA in health and disease. Its high specificity and sensitivity ensure reliable detection and analysis of REV-ERB BETA protein levels in various cell and tissue samples, contributing to the advancement of knowledge in the fields of chronobiology, metabolism, and drug development.
Product Name:
Rev-erb beta/NR1D2 Monoclonal Antibody
SKU:
CAB22050
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human Rev-erb beta/NR1D2 (NP_005117.3).
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
9975
Clone Number:
ARC54887
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Rev-erb beta/NR1D2 Rabbit mAb (CAB22050) at1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
