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Retinoid X Receptor gamma Transcription Factor Activity Assay

SKU:
TFAB00176
Product Type:
ELISA Kit
ELISA Type:
Transcription Factor Assay
Analytes:
Retinoid X Receptor gamma
Reactivity:
Human
Mouse
€599
Frequently bought together:

Description

system_update_altDatasheet

Retinoid X Receptor gamma Transcription Factor Activity Assay

The Retinoid X Receptor Gamma Transcription Factor Activity Assay kit from AssayGenie is a powerful tool for studying the activity of the retinoid X receptor gamma transcription factor. This kit is designed for accurate detection and quantification of RXR gamma activity in cell lysates, serum, plasma, and tissue homogenates.The assay features high sensitivity and specificity, ensuring reliable and reproducible results for your research needs. The Retinoid X Receptor Gamma Transcription Factor Activity Assay kit is ideal for investigating the role of RXR gamma in gene regulation, cell differentiation, and various diseases such as cancer, diabetes, and metabolic disorders.

By using this assay kit, researchers can gain valuable insights into the biological functions of RXR gamma and potentially identify new therapeutic targets for treating diseases associated with dysregulated retinoid signaling. Upgrade your research with the Retinoid X Receptor Gamma Transcription Factor Activity Assay kit from AssayGenie.

Product Name:Retinoid X Receptor gamma Transcription Factor Activity Assay
Product Code:TFAB00176
Target:Retinoid X Receptor gamma
Reactivity:Human, Mouse
Sample Types:Nuclear or cell lysates

The Assay Genie Retinoid X Receptor gamma transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates

Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.

Assay Time:4.5 hours
Detection Method:Colorimetric 450 nm
Size:12 x 8-Well Microstrips
Storage:4°C for 6 months
UniProt Protein Function:RXRG: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. Homodimer. Heterodimer with a RAR molecule. Binds DNA preferentially as a RAR/RXR heterodimer. Belongs to the nuclear hormone receptor family. NR2 subfamily.
UniProt Protein Details:

Protein type:DNA-binding; Nuclear receptor

Chromosomal Location of Human Ortholog: 1q22-q23

Cellular Component: nucleoplasm

Molecular Function:protein binding; zinc ion binding; retinoid-X receptor activity; steroid hormone receptor activity

Biological Process: retinoic acid receptor signaling pathway; neuron differentiation; transcription initiation from RNA polymerase II promoter; skeletal muscle development; response to retinoic acid; regulation of myelination; heart development; steroid hormone mediated signaling; gene expression; transmembrane transport; protein homotetramerization; peripheral nervous system development

NCBI Summary:This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]
UniProt Code:P48443
NCBI GenInfo Identifier:1350913
NCBI Gene ID:6258
NCBI Accession:P48443.1
UniProt Secondary Accession:P48443,Q6IBU7, A6NIP1,
UniProt Related Accession:P48443
Molecular Weight:50,871 Da
NCBI Full Name:Retinoic acid receptor RXR-gamma
NCBI Synonym Full Names:retinoid X receptor, gamma
NCBI Official Symbol:RXRG  
NCBI Official Synonym Symbols:RXRC; NR2B3  
NCBI Protein Information:retinoic acid receptor RXR-gamma; nuclear receptor subfamily 2 group B member 3
UniProt Protein Name:Retinoic acid receptor RXR-gamma
UniProt Synonym Protein Names:Nuclear receptor subfamily 2 group B member 3; Retinoid X receptor gamma
UniProt Gene Name:RXRG  
UniProt Entry Name:RXRG_HUMAN
Antibodies
Anti-RXRG Antibody (CAB1877)
RXRG Antibody (PACO06807)
RXRG Antibody (PACO11997)
RXRG Antibody (PACO47626)
RXRG Antibody, HRP conjugated (PACO47627)

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