The RERG Antibody (PAC011803) is a high-quality polyclonal antibody designed for research involving RERG, a protein known to play a role in various cellular processes. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. It binds specifically to the RERG protein, allowing for accurate detection and analysis in a variety of cell types.RERG, also known as Ras-related and estrogen-regulated growth inhibitor, is involved in regulating cell growth, differentiation, and migration.
Dysregulation of RERG expression has been implicated in cancer progression, making it a potential target for cancer research. Additionally, RERG has been linked to estrogen signaling pathways, suggesting a potential role in hormone-related disorders.This antibody is ideal for studies in cell biology, cancer research, and hormone signaling pathways. By understanding the function and regulation of RERG, researchers can gain valuable insights into its role in various diseases and potentially develop targeted therapies in the future.
RERG: Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential. Belongs to the small GTPase superfamily. Ras family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: G protein, monomeric; G protein; G protein, monomeric, RasChromosomal Location of Human Ortholog: 12p12.3Cellular Component: membrane; cytosol; nucleusMolecular Function: GTPase activity; GDP binding; GTP binding; estrogen receptor bindingBiological Process: negative regulation of cell proliferation; metabolic process; small GTPase mediated signal transduction; response to hormone stimulus; negative regulation of cell growth
