The RERG Antibody (PACO05553) is a polyclonal antibody designed for research involving RERG, a protein implicated in immune regulation and cancer development. The antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in Western blot applications. RERG, also known as Ras-like estrogen regulated growth inhibitor, plays a critical role in regulating cell growth and differentiation, particularly in cancer cells. Its involvement in cancer development and progression makes it a valuable target for research into cancer therapies and treatments.
Understanding the function of RERG is essential for developing targeted therapies that can inhibit its activity and prevent cancer growth.The RERG Antibody (PACO05553) enables detection and analysis of RERG protein in various cell types, providing researchers with a valuable tool for studying the role of RERG in cancer and immune regulation. Its specificity and sensitivity make it a reliable choice for studies in oncology and immunology research.
Antibody Name:
RERG Antibody (PACO05553)
Antibody SKU:
PACO05553
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:5000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from the Internal region of human RERG.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
RERG; Ras-related and estrogen-regulated growth inhibitor
UniProt Protein Function:
RERG: Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential. Belongs to the small GTPase superfamily. Ras family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: G protein, monomeric; G protein; G protein, monomeric, RasChromosomal Location of Human Ortholog: 12p12.3Cellular Component: membrane; cytosol; nucleusMolecular Function: GTPase activity; GDP binding; GTP binding; estrogen receptor bindingBiological Process: negative regulation of cell proliferation; metabolic process; small GTPase mediated signal transduction; response to hormone stimulus; negative regulation of cell growth
