The Reptin/RuvBL2 Rabbit Monoclonal Antibody (CAB4227) is a cutting-edge tool for researchers studying the Reptin/RuvBL2 protein, which plays a crucial role in various cellular processes including transcriptional regulation, DNA repair, and chromatin remodeling. This highly specific antibody, developed using rabbit monoclonal technology, offers exceptional reactivity with human samples and is validated for use in Western blot applications.The Reptin/RuvBL2 protein, also known as Pontin or TIP49, is a key component of many protein complexes involved in regulating gene expression and maintaining genomic stability. Its involvement in essential cellular functions makes it a promising target for research in fields such as cancer biology, cell biology, and genomics.
By enabling the detection and analysis of Reptin/RuvBL2 in different cell types, this antibody provides valuable insights into the mechanisms underlying various diseases and biological processes.Researchers exploring the molecular mechanisms of gene regulation, DNA repair, and chromatin remodeling will find the Reptin/RuvBL2 Rabbit Monoclonal Antibody to be a valuable asset in their investigations. Its high specificity and sensitivity make it an indispensable tool for unraveling the complex roles of the Reptin/RuvBL2 protein in health and disease, paving the way for novel therapeutic strategies and diagnostic approaches.
Product Name:
Reptin/RUVBL2 Rabbit Monoclonal Antibody
SKU:
CAB4227
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human Reptin/RUVBL2 (Q9Y230).
This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
Purification Method:
Affinity purification
Gene ID:
10856
Clone Number:
ARC0933
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Reptin/RUVBL2 Rabbit mAb (CAB4227) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
