Ren2 Antibody (PACO33764)
- SKU:
- PACO33764
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Ren2 Antibody (PACO33764)
The REN2 Polyclonal Antibody (PACO33764) is a valuable tool for researchers studying the REN2 protein, which is involved in immune regulation processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the REN2 protein, this antibody enables researchers to detect and analyze REN2 in various cell types, making it ideal for studies in immunology and cancer research.REN2, also known as a immune regulatory molecule, plays a crucial role in immune homeostasis by modulating immune responses and inhibiting inflammation.
Its involvement in immune regulation makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of REN2 is essential for developing potential therapies that target or modulate immune responses in these disease contexts.
| Antibody Name: | Ren2 Antibody (PACO33764) |
| Antibody SKU: | PACO33764 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Mouse, Human |
| Immunogen: | Recombinant Mouse Renin-2 protein (64-351AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Ren2 antibody at 2µg/ml + MCF-7 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 45 kDa Observed band size: 45 kDa . |
 | Western Blot Positive WB detected in: Mouse kidney tissue All lanes: Ren2 antibody at 4µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 45 kDa Observed band size: 45 kDa . |
| Background: | Renin is a highly specific endopeptidase, related to pepsin, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Its function in the salivary gland is not understood. |
| Synonyms: | Renin-2 (EC 3.4.23.15) (Angiotensinogenase) (Submandibular gland renin) [Cleaved into: Renin-2 heavy chain; Renin-2 light chain], Ren2, Ren-2 |
| UniProt Protein Function: | Renin is a highly specific endopeptidase, related to pepsin, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Its function in the salivary gland is not understood. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P00796 |
| NCBI GenInfo Identifier: | 118150650 |
| NCBI Gene ID: | 19702 |
| NCBI Accession: | NP_112470.2 |
| UniProt Secondary Accession: | P00796,P70229, P97955, Q62155 |
| UniProt Related Accession: | P00796 |
| Molecular Weight: | 35 kDa |
| NCBI Full Name: | renin-2 |
| NCBI Synonym Full Names: | renin 2 tandem duplication of Ren1 |
| NCBI Official Symbol: | Ren2Â Â |
| NCBI Official Synonym Symbols: | Ren; Rnr; Rn-2; Ren-2; Ren-BÂ Â |
| NCBI Protein Information: | renin-2 |
| UniProt Protein Name: | Renin-2 |
| UniProt Synonym Protein Names: | Angiotensinogenase; Submandibular gland renin |
| Protein Family: | Renin |
| UniProt Gene Name: | Ren2Â Â |
| UniProt Entry Name: |
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