The REM1 Polyclonal Antibody (PAC058865) is a valuable tool for researchers studying REM1, a protein involved in various cellular processes, including cell growth and differentiation. This antibody, produced in rabbits, exhibits high specificity for REM1 in human samples and is suitable for use in Western blot applications. By targeting the REM1 protein, researchers can accurately detect and analyze its expression in different cell types, making it an ideal choice for research in cell biology and cancer studies.
REM1 is known to play a crucial role in cellular signaling pathways and has been implicated in the development and progression of various diseases, including cancer. By investigating the function of REM1, researchers can gain insights into its potential as a therapeutic target for treating cancer and other related conditions. Overall, the REM1 Polyclonal Antibody is a valuable tool for studying the role of REM1 in cellular processes and disease development.
Antibody Name:
REM1 Antibody (PACO58865)
Antibody SKU:
PACO58865
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human GTP-binding protein REM 1 protein (2-153AA)
Immunofluorescence staining of HepG2 cells with PACO58865 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling.
Synonyms:
GTP-binding protein REM 1 (GTPase-regulating endothelial cell sprouting) (Rad and Gem-like GTP-binding protein 1), REM1, GES REM
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a GTPase and member of the RAS-like GTP-binding protein family. The encoded protein is expressed in endothelial cells, where it promotes reorganization of the actin cytoskeleton and morphological changes in the cells. [provided by RefSeq, Jul 2008]
