The RELT Polyclonal Antibody (CAB15540) is a valuable tool for researchers studying the role of RELT, a TNF receptor molecule involved in immune signaling pathways. This antibody, produced using rabbit immunization, displays high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the RELT protein, this antibody enables accurate detection and analysis across various cell types, making it an excellent choice for investigations in immunology and cancer research.RELT, also known as TNFRSF19L, is a key player in immune regulation, with potential implications in the development of therapeutic strategies for immune-related diseases such as cancer and autoimmune disorders.
Its involvement in immune responses and inflammation underscores its importance as a target for further research aimed at understanding and manipulating immune function. With the RELT Polyclonal Antibody, researchers can uncover new insights into the mechanisms underlying immune system modulation and disease progression.
Product Name:
RELT Rabbit Polyclonal Antibody
SKU:
CAB15540
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-162 of human RELT (NP_116260.2).
Cell membrane, Cytoplasm, Single-pass type I membrane protein.
Calculated MW:
46kDa
Observed MW:
47kDa
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
Purification Method:
Affinity purification
Gene ID:
84957
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RELT Rabbit pAb (CAB15540) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60S.
