RELN Rabbit Polyclonal Antibody (CAB17936)
- SKU:
- CAB17936
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | RELN Rabbit Polyclonal Antibody |
SKU: | CAB17936 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-190 of human RELN (NP_005036.2). |
Sequence: | KIST KNPD FLKD DFEG QLES DRFL LMSG GKPS RKCG ILSS GNNL FFNE DGLR MLMT RDLD LSHA RFVQ FFMR LGCG KGVP DPRS QPVL LQYS LNGG LSWS LLQE FLFS NSSN VGRY IALE IPLK ARSG STRL RWWQ PSEN GHFY SPWV IDQI LIGG NISG N |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | RL; ETL7; LIS2; PRO1598; RELN |
Positive Sample: | U-87MG,C6,LO2,HepG2 |
Cellular Localization: | cytoplasm, dendrite, extracellular region, extracellular space, neuron projection, plasma membrane, reelin complex |
Calculated MW: | 388kDa |
Observed MW: | 180kDa/388kDa |
This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 5649 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |