The Regucalcin Polyclonal Antibody (CAB3350) is a powerful research tool designed for studies involving Regucalcin, a protein known for its role in regulating intracellular calcium homeostasis and cell signaling pathways. This antibody, derived from rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Regucalcin, also referred to as senescence marker protein-30 (SMP30), is a multifunctional protein that plays a vital role in various physiological processes, including cell proliferation, apoptosis, and oxidative stress response. Its involvement in cellular signaling pathways makes it a valuable target for research in fields such as molecular biology, biochemistry, and aging studies.By utilizing the Regucalcin Polyclonal Antibody (CAB3350), researchers can effectively detect and analyze Regucalcin protein levels in different cell types, shedding light on its function in cellular processes.
This antibody is an ideal tool for investigating the mechanisms underlying calcium regulation and signaling pathways, providing valuable insights into potential therapeutic targets for conditions related to calcium dysregulation and cellular dysfunction.Overall, the Regucalcin Polyclonal Antibody (CAB3350) serves as a critical resource for researchers exploring the role of Regucalcin in various biological processes, offering a reliable and specific tool for advancing understanding in the fields of molecular biology, cell biology, and aging research.
Product Name:
RGN Rabbit Polyclonal Antibody
SKU:
CAB3350
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human RGN (NP_004674.1).
The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9104
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RGN antibody (CAB3350) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
