The REG3G Polyclonal Antibody (CAB2146) is a valuable tool for researchers studying REG3G, a protein with important implications in immune regulation and inflammatory response. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in various applications including Western blotting.REG3G is a member of the regenerating islet-derived (REG) gene family and is involved in the regulation of immune responses and inflammation.
Its expression has been linked to various diseases such as inflammatory bowel disease and cancer, making it a promising target for further investigation.By using the REG3G Polyclonal Antibody, researchers can efficiently detect and analyze REG3G protein levels in different cell types, allowing for a better understanding of its role in disease pathology. This antibody is a valuable resource for studies in immunology, cancer research, and inflammatory conditions.
Product Name:
REG3G Rabbit Polyclonal Antibody
SKU:
CAB2146
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 27-174 of mouse REG3G (NP_035390.1).
This gene encodes a C-type lectin that demonstrates bactericidal activity. This gene is predominantly expressed in the distal small intestine where the encoded protein undergoes proteolytic processing by trypsin. Mice lacking the encoded protein exhibit altered mucus distribution, increased bacterial contact with the epithelium, and elevated inflammatory markers in the ileum, and low-grade inflammation.
Purification Method:
Affinity purification
Gene ID:
19695
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using REG3G antibody (CAB2146) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
