Reg3g Antibody (PACO29452)
- SKU:
- PACO29452
- Product Type:
- Antibody
- Reactivity:
- Rat
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Reg3g Antibody (PACO29452)
The REG3G Polyclonal Antibody (PAC029452) is a valuable tool for researchers studying REG3G, a protein involved in immune regulation and inflammatory responses. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to REG3G, this antibody allows for the detection and analysis of REG3G protein levels in various cell types, making it an essential component of studies in immunology and inflammatory diseases.
REG3G, also known as a secreted C-type lectin, is involved in regulating the balance between inflammatory and anti-inflammatory responses in the immune system. Its role in inflammation and immune response modulation makes it an important target for research into diseases such as inflammatory bowel disease, autoimmune disorders, and cancer. Understanding the function of REG3G is critical for developing targeted therapies that can manipulate immune responses in these disease contexts.
| Antibody Name: | Reg3g Antibody (PACO29452) |
| Antibody SKU: | PACO29452 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Rat, Mouse |
| Immunogen: | Recombinant Rat Regenerating islet-derived protein 3-γ protein (27-174AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Reg3g antibody at 14µg/ml + Mouse kidney tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 20 kDa Observed band size: 20 kDa . |
| Background: | Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury (By similarity). |
| Synonyms: | Regenerating islet-derived protein 3-γ (REG-3-gamma) (Pancreatitis-associated protein 3) (Regenerating islet-derived protein III-gamma) (Reg III-gamma) [Cleaved into: Regenerating islet-derived protein 3-γ 16.5 kDa form; Regenerating islet-derived protein 3-γ 15 kDa form], Reg3g, Pap3 |
| UniProt Protein Function: | Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P42854 |
| NCBI GenInfo Identifier: | 27465527 |
| NCBI Gene ID: | 24620 |
| NCBI Accession: | NP_775120.1 |
| UniProt Secondary Accession: | P42854 |
| UniProt Related Accession: | P42854 |
| Molecular Weight: | 18.3 kDa |
| NCBI Full Name: | regenerating islet-derived protein 3-gamma |
| NCBI Synonym Full Names: | regenerating family member 3 gamma |
| NCBI Official Symbol: | Reg3g  |
| NCBI Official Synonym Symbols: | Pap3; PAPIIIÂ Â |
| NCBI Protein Information: | regenerating islet-derived protein 3-gamma |
| UniProt Protein Name: | Regenerating islet-derived protein 3-gamma |
| UniProt Synonym Protein Names: | Pancreatitis-associated protein 3; Regenerating islet-derived protein III-gamma; Reg III-gamma |
| Protein Family: | Regenerating islet-derived protein |
| UniProt Gene Name: | Reg3g  |
| UniProt Entry Name: | REG3G_RAT |
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