REG3G Antibody (PACO16679)
- SKU:
- PACO16679
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
REG3G Antibody (PACO16679)
The REG3G Polyclonal Antibody (PAC016679) is a valuable tool for researchers studying REG3G, a protein involved in immune regulation and inflammation. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the REG3G protein, researchers can analyze its expression and function in various cell types, making it ideal for investigations in immunology and inflammatory diseases.REG3G, also known as regenerating islet-derived protein 3 gamma, plays a crucial role in maintaining immune homeostasis by regulating inflammatory responses and promoting tissue repair.
Its involvement in immune modulation makes it a promising target for research on diseases such as cancer, autoimmune conditions, and inflammatory disorders. Understanding the role of REG3G is essential for developing new therapies that target immune dysregulation in these pathological conditions.
| Antibody Name: | REG3G Antibody (PACO16679) |
| Antibody SKU: | PACO16679 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human REG3G |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16679(REG3G Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human brain malignant glioma tissue, mouse kidney tissue, human kidney tissue, Primary antibody: PACO16679(REG3G Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO16679(REG3G Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a member of the regenerating islet-derived genes (REG)3 protein family. These proteins are secreted, C-type lectins with a carbohydrate recognition domain and N-terminal signal peptide. The protein encoded by this gene is an antibacterial lectin with activity against Gram-positive bacteria. Alternative splicing results in multiple transcript variants encoding multiple isoforms. |
| Synonyms: | regenerating islet-derived 3 gamma |
| UniProt Protein Function: | REG3G: Might be a stress protein involved in the control of bacterial proliferation. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 2p12 Cellular Component: cytoplasm; extracellular region Molecular Function:peptidoglycan binding Biological Process: acute-phase response; antimicrobial humoral response; cytolysis in other organism; defense response to Gram-positive bacterium; MyD88-dependent toll-like receptor signaling pathway; negative regulation of keratinocyte differentiation |
| NCBI Summary: | This gene encodes a member of the regenerating islet-derived genes (REG)3 protein family. These proteins are secreted, C-type lectins with a carbohydrate recognition domain and N-terminal signal peptide. The protein encoded by this gene is an antimicrobial lectin with activity against Gram-positive bacteria. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Nov 2014] |
| UniProt Code: | Q6UW15 |
| NCBI GenInfo Identifier: | 56699413 |
| NCBI Gene ID: | 130120 |
| NCBI Accession: | NP_001008388.1 |
| UniProt Secondary Accession: | Q6UW15,Q3SYE4, Q3SYE6, Q6FH18, A8K980, D6W5J6, |
| UniProt Related Accession: | Q6UW15 |
| Molecular Weight: | |
| NCBI Full Name: | regenerating islet-derived protein 3-gamma isoform 1 preproprotein |
| NCBI Synonym Full Names: | regenerating family member 3 gamma |
| NCBI Official Symbol: | REG3GÂ Â |
| NCBI Official Synonym Symbols: | PAP1B; PAPIB; PAP IB; PAP-1B; UNQ429; LPPM429; REG III; REG-IIIÂ Â |
| NCBI Protein Information: | regenerating islet-derived protein 3-gamma |
| UniProt Protein Name: | Regenerating islet-derived protein 3-gamma |
| UniProt Synonym Protein Names: | Pancreatitis-associated protein 1B; PAP-1B |
| Protein Family: | Regenerating islet-derived protein |
| UniProt Gene Name: | REG3GÂ Â |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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