The REG3B Polyclonal Antibody (PACO34350) is a powerful tool for researchers studying REG3B, a protein involved in immune regulation and intestinal homeostasis. This antibody is produced using rabbits and has been carefully validated for Western blot applications with human samples.REG3B, a member of the REG protein family, is known for its antimicrobial properties and its role in maintaining the integrity of the intestinal barrier. Dysregulation of REG3B has been linked to various gastrointestinal disorders, making it an important target for research in gut health and disease.
By using the REG3B Polyclonal Antibody, researchers can detect and analyze REG3B expression in different cell types, providing valuable insights into its function and potential therapeutic applications. This antibody is a valuable tool for studies in immunology, microbiology, and gastrointestinal research, offering new possibilities for understanding and treating intestinal diseases.
Antibody Name:
Reg3b Antibody (PACO34350)
Antibody SKU:
PACO34350
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Rat
Immunogen:
Recombinant Rat Regenerating islet-derived protein 3-β protein (27-175AA)
Bactericidal C-type lectin which acts against several intestinal Gram-positive bacteria and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues (By similarity).
Synonyms:
Regenerating islet-derived protein 3-β (REG-3-beta) (Pancreatitis-associated protein 1) (Peptide 23) (REG-2) (Regenerating islet-derived protein III-beta) (Reg III-beta) [Cleaved into: Regenerating islet-derived protein 3-β 16.5 kDa form; Regenerating islet-derived protein 3-β 15 kDa form], Reg3b, Pap Pap1 Reg2
UniProt Protein Function:
Bactericidal C-type lectin which acts against several intestinal Gram-positive bacteria and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues.
NCBI Summary:
lectin-related secretory protein; may be involved in stress response to control bacterial proliferation during acute pancreatitis [RGD, Feb 2006]
