Reg3a Antibody (PACO29448)
- SKU:
- PACO29448
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Reg3a Antibody (PACO29448)
The REG3A Polyclonal Antibody (PAC029448) is a valuable tool for research on REG3A, a protein involved in immune regulation and tissue homeostasis. This antibody, raised in rabbits, is highly specific for human REG3A and has been validated for use in Western blot applications.REG3A is a secreted C-type lectin that plays a role in modulating immune responses and maintaining intestinal barrier function. Abnormal REG3A expression has been linked to inflammatory disorders, making it a potential therapeutic target for conditions such as inflammatory bowel disease and colorectal cancer.
By using the REG3A Polyclonal Antibody, researchers can accurately detect and quantify REG3A in various cell types and tissues, providing valuable insights into its function and potential as a biomarker or therapeutic target. This antibody is a valuable tool for studies in immunology, gastrointestinal health, and cancer research.
| Antibody Name: | Reg3a Antibody (PACO29448) |
| Antibody SKU: | PACO29448 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Regenerating islet-derived protein 3-α protein (26-174AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Bactericidal C-type lectin. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway (By similarity). |
| Synonyms: | Regenerating islet-derived protein 3-α (REG-3-alpha) (Islet of Langerhans regenerating protein 3) (REG 3) (Lithostathine 3) (Pancreatitis-associated protein 2) (RegIII) (Regenerating islet-derived protein III-alpha) (Reg III-alpha) [Cleaved into: Regenerating islet-derived protein 3-α 16.5 kDa form; Regenerating islet-derived protein 3-α 15 kDa form], Reg3a, Pap2 Reg3 |
| UniProt Protein Function: | REG3A: Might be a stress protein involved in the control of bacterial proliferation. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Cellular Component: extracellular region Molecular Function:carbohydrate binding Biological Process: acute-phase response; negative regulation of keratinocyte differentiation |
| NCBI Summary: | lectin-related secretory protein; overexpressed during the acute phase of pancreatitis [RGD, Feb 2006] |
| UniProt Code: | P35231 |
| NCBI GenInfo Identifier: | 224994175 |
| NCBI Gene ID: | 171162 |
| NCBI Accession: | NP_001139318.1 |
| UniProt Related Accession: | P35231 |
| Molecular Weight: | 20.5 kDa |
| NCBI Full Name: | regenerating islet-derived protein 3-alpha |
| NCBI Synonym Full Names: | regenerating islet-derived 3 alpha |
| NCBI Official Symbol: | Reg3a  |
| NCBI Official Synonym Symbols: | Pap2; PapIIÂ Â |
| NCBI Protein Information: | regenerating islet-derived protein 3-alpha |
| UniProt Protein Name: | Regenerating islet-derived protein 3-alpha |
| UniProt Synonym Protein Names: | Islet of Langerhans regenerating protein 3; REG 3 |
| Protein Family: | Regenerating islet-derived protein |
| UniProt Gene Name: | Reg3a  |
| UniProt Entry Name: | REG3A_RAT |
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