The REG1A Polyclonal Antibody (CAB5327) is a vital tool for researchers studying REG1A, a protein involved in cell growth and differentiation. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting REG1A in human samples, making it an excellent choice for Western blot applications. By binding to REG1A, this antibody enables the precise identification and analysis of REG1A protein levels in various cell types, facilitating research in areas such as cancer biology, developmental biology, and regenerative medicine.
REG1A, also known as Regenerating islet-derived protein 1 alpha, is a key player in regulating cell proliferation and tissue regeneration, with implications in cancer progression and wound healing. Its versatile functions in cell growth and tissue repair make it a promising target for investigating fundamental biological processes and disease mechanisms. By studying REG1A expression and activity, researchers can gain valuable insights into the molecular pathways underlying cell development and disease progression.
Product Name:
REG1A Rabbit Polyclonal Antibody
SKU:
CAB5327
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human REG1A (NP_002900.2).
This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.
Purification Method:
Affinity purification
Gene ID:
5967
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using REG1A antibody (CAB5327) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (AbGn00020)._Exposure time: 60s.
