Reference Biosimilar Antibodies
Reference Biosimilar Antibodies
Functional-grade biosimilars optimized for in vitro investigations and comparison studies!
Why choose Reference Biosimilars?
- Definition | Designed to be nearly identical to an original (reference) biologic medicine, used in research or preclinical studies
- Purpose | Serve as research tools without requiring access to the proprietary original biologic
- Non-therapuetic | Strictly for research use only (RUO)
- Applications | Validated for ELISAs, FC, WB & more
Popular Reference Biosimilars
Testimonials & Partners
"I ordered from AssayGenie for the first time and would like to share my satisfied impression. The article (Bevacizumab; IVMB0232) was used as a positive control and works excellently in Biacore SPR measurements and VEGF bioassay"
- G. Carsten, Fraunhofer (2024)
Delivery in 7-10 business days
24 hours on LiveChat & PhD level support
Cost-effective alternative to therapeutic mAbs
ISO Certification
Quality is at the core of everything we do.
Manufactured in state-of-the-art facilities, our products meet the highest standards, including ISO 9001:2015 certification. This ensure consistent quality, customer-focused innovation, and reliable performance in every batch.
Reference Biosimilar Data
Reference Biosimilars
Our Reference & Conjugated Biosimilars demonstrate exceptional performance in research assays. The ELISA assay on the left highlights a dose-dependent response using 0.2 µg of human TNF-α per well, confirming strong binding activity and neutralizing capabilities of the biosimilar.
Meet Some of the Genie Team!
At Assay Genie, we're here to help every step of the way. Whether you need guidance choosing the right product, updates on your order, or expert support after your purchase, we've got you covered.
Shane, Sales
Natalia, Tech Support
Chris, Sales
Beatriz, Logistics
Marina, Tech Support
Miren, Sales
José, Sales
David, Sales
Joe, Sales
Shivaun, Logistics
Vinothini, Data Analyst
Bala, Data Analyst
Frequently Asked Questions
Research-grade biosimilars are laboratory-produced proteins that are designed to mimic the structure and function of approved biologic drugs. They are used in preclinical studies, assay development, and other non-clinical applications.
Research-grade biosimilars are intended for laboratory and research purposes only. They are not subject to the same regulatory scrutiny as therapeutic biosimilars, which must undergo clinical trials and approval processes for patient use.
No, research-grade biosimilars are designed to be similar in structure and function to reference biologics but are not identical. They are primarily used for assay development, drug screening, and in vitro/in vivo research.
They may be produced in similar systems (e.g., CHO cells, E. coli, yeast), but there can be differences in post-translational modifications, glycosylation patterns, or impurities.
Quality is assessed through purity analysis (SDS-PAGE, HPLC, Mass Spectrometry), bioactivity assays, and binding affinity tests (e.g., ELISA, SPR, BLI).
- Preclinical drug screening
- Assay development and validation (e.g., ELISA, Western Blot, Flow Cytometry)
- Mechanism of action studies
- Comparative studies against reference biologics
Yes, they can be used in in vivo models to study pharmacokinetics, pharmacodynamics, and efficacy before moving to clinical-grade biosimilars.
Biosimilar Resources - Blogs & Podcast Episodes
Quick Facts About EnavatuzumabWhat is Enavatuzumab?Enavatuzumab is a monoclonal antibody targeting the TWEAK receptor (Fn14), pivotal in tumor growth and immune regulation.What is the mechanism of action for Enavatuzumab?Enavatuzumab binds to Fn14, inhibiting signaling pathways that promote tumor cell proliferation and survival while [...]Quick Facts About EnavatuzumabWhat is Enavatuzumab?Enavatuzumab is a monoclonal antibody targeting the TWEAK receptor (Fn14), pivotal in tumor growth and immune regulation.What is the mechanism of action for Enavatuzumab?Enavatuzumab binds to Fn14, inhibiting signaling pathways that promote tumor cell proliferation and survival while [...]
Quick Facts About SiltuximabWhat is Siltuximab?Siltuximab is a monoclonal antibody targeting interleukin-6 (IL-6), a cytokine involved in inflammation and immune regulation.What is the mechanism of action for Siltuximab?Siltuximab binds to IL-6, preventing it from interacting with its receptor and mitigating downstream pro-inflammatory signaling.What [...]
Related Products
Additional Resources
