The REEP1 Polyclonal Antibody (CAB7832) is a vital tool for researchers studying REEP1, a protein involved in shaping and maintaining the structure of the endoplasmic reticulum in cells. This antibody, produced in rabbits, has high specificity for detecting REEP1 in human samples and is validated for use in Western blot applications. By binding to the REEP1 protein, this antibody enables precise detection and analysis in various cell types, making it essential for research in cell biology and neurodegenerative diseases.REEP1 is a critical player in maintaining the structure and function of the endoplasmic reticulum, a crucial organelle involved in protein synthesis and lipid metabolism.
Dysregulation of REEP1 has been implicated in diseases like hereditary spastic paraplegia, where defects in endoplasmic reticulum shape and function lead to neurodegeneration. By studying the role of REEP1, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention. Unlock the potential of your research with the REEP1 Polyclonal Antibody (CAB7832) from Assay Genie.
Product Name:
REEP1 Rabbit Polyclonal Antibody
SKU:
CAB7832
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 101-201 of human REEP1 (NP_075063.1).
This gene encodes a mitochondrial protein that functions to enhance the cell surface expression of odorant receptors. Mutations in this gene cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
65055
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using REEP1 antibody (CAB7832) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
