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Rat TIM1/HACVR1 Recombinant Protein (RPES1597)

SKU:
RPES1597
Product Type:
Recombinant Protein
Species:
Rat
€540
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Description

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Rat TIM1/HACVR1 Recombinant Protein

HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â…  integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.

Product Name:Rat TIM1/HACVR1 Recombinant Protein (RPES1597)
Product Code:RPES1597
Size:20µg
Species:Rat
Expressed Host:HEK293 Cells
Synonyms:KIM-1,Kim1,Havcr1
Accession:NP_775172.1
Sequence:Ser 18-Val 238
Fusion tag:C-His & N-Fc
Endotoxin:<1.0 EU per µg of the protein as determined by the LAL method
Protein Construction:A DNA sequence encoding the extracellular domain of rat HAVCR1 (NP_775172.1) (Ser 18-Val 238) was fused with a polyhistidine tag at the C-terminus and the Fc region of human IgG1 at the N-terminus.
Purity:> 93 % as determined by SDS-PAGE
Mol Mass:52.6 kDa
AP Mol Mass:90-100 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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