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Rat Thrombomodulin Recombinant Protein (RPES4057)

SKU:
RPES4057
Product Type:
Recombinant Protein
Species:
Rat
€1,190
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Description

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Rat Thrombomodulin Recombinant Protein

Thrombomodulin, also known as THBD(CD141), is an integral membrane protein which reduces blood coagulation by converting thrombin to an anticoagulant enzyme from a procoagulant enzyme. Thrombomodulin is expressed on the surface of endothelial cells and serves as a cofactor for thrombin. It is also expressed on human mesothelial cell, monocyte and a dendritic cell subset. Thrombomodulin functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming a 1:1 stoichiometric complex with thrombin. Thrombomodulin also regulates C3b inactivation by factor I. Mutations in the thrombomodulin gene have also been reported to be associated with atypical hemolytic-uremic syndrome.

Product Name:Rat Thrombomodulin Recombinant Protein (RPES4057)
Product Code:RPES4057
Size:10µg
Species:Rat
Expressed Host:HEK293 Cells
Synonyms:THBD
Accession:O35370
Sequence:Met1-Ser517
Fusion tag:C-His
Endotoxin:<1.0 EU per µg of the protein as determined by the LAL method
Protein Construction:A DNA sequence encoding the rat THBD (O35370) (Met1-Ser517) was expressed with a polyhistidine tag at the C-terminus.
Purity:> 90 % as determined by SDS-PAGE
Mol Mass:55.2 kDa
AP Mol Mass:95 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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