Recombinant Rat IL-3 Protein (RPCB1205)
- SKU:
- RPCB1205
- Size:
- 10µg
- Tag:
- C-His
- Reactivity:
- Rat
- Expression Host:
- HEK293 cells
Description
| Product Name: | Recombinant Rat IL-3 Protein |
| SKU: | RPCB1205 |
| Size: | 10µg |
| Tag: | C-His |
| Reactivity: | Rat |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Rat IL-3 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 0.1EU/μg |
| Purity: | > 97% by SDS-PAGE. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Gene ID: | 24495 |
IL3 (interleukin 3), also known as IL-3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation, and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | P97688 |
 | Recombinant Rat IL-3 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 25-35 kDa. |
 | Recombinant Rat IL-3 stimulates cell proliferation of the NFS_x0000_60 mouse myelogenous leukemia lymphoblast cells. The ED₅₀ for this effect is 2.6_x0000_10.6 ng/mL,corresponding to a specific activity of 9.4×104~3.85×105 units/mg. |
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