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Recombinant Mouse TNFSF12/TWEAK Protein (RPCB1730)

SKU:
RPCB1730
Size:
50µg
Tag:
C-raFc
Reactivity:
Mouse
Expression Host:
HEK293 Cells
€349

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Mouse TNFSF12/TWEAK Protein
SKU:RPCB1730
Size:50µg
Tag:C-raFc
Reactivity:Mouse
Expression Host:HEK293 Cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Mouse TNFSF12/TWEAK Protein , tested reactivity in HEK293 Cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:<1EU/μg
Purity:> 90% by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Gene ID:21944

TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue distribution. It can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. It is also found that TNFSF12 promotes proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. TNFSF12 also is a weak inducer of apoptosis in some cell types and mediates NF-kappa-B activation.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:O54907
Product ImageRecombinant Mouse TNFSF12/TWEAK Protein was determined by SDS-PAGE with Coomassie Blue, showing bands at 45 kDa.
Product ImageRecombinant Mouse TNFSF12 promotes the proliferation of human umbilical vein endothelial cells (HUVEC). The EDâ‚…â‚€ for this effect is typically 10-50 ng/mL.

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