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Recombinant Mouse TNF Receptor II/TNF RII/TNFRSF1B/CD120b (C-Fc) (RPES6676)

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SKU:
RPES6676
Product Type:
Recombinant Protein
Species:
Mouse
€229

Description

Product Name:Recombinant Mouse TNF Receptor II/TNF RII/TNFRSF1B/CD120b (C-Fc)
Product Code:RPES6676
Size:10µg
Species:Mouse
Expression Host:HEK293 Cells
Synonyms:TNF-RII, TNFRII, TNF RII, Tumor necrosis factor receptor superfamily member 1b, Tnfrsf1b
Mol Mass:52.3 kDa
AP Mol Mass:60-85 kDa
Tag:C-Fc
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:Val23-Gly258
Accession:Q545P4
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains: Tumor necrosis factor receptor superfamily member 1b and membrane form and Tumor necrosis factor-binding protein 2. TNFRSF1B is a receptor with high affinity for TNFSF2/TNF-α and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-α. TNFRSF1B mediates most of the metabolic effects of TNF-α. TNF-α-induced apoptosis suggests that it regulates TNF-α function by antagonizing its biological activity.

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