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Mouse TNF-alpha/TNFA Recombinant Protein ((RPES3592)

SKU:
RPES3592
Product Type:
Recombinant Protein
Species:
Mouse
Research Area:
Growth Factors & Cytokines
$283
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Description

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Mouse TNF-alpha/TNFA Recombinant Protein (

Tumor Necrosis Factor (TNF) is a member of the Tumor Necrosis Factor family. TNF exists as a homotrimer and interacts with SPPL2B. TNF is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. TNF is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes throught its effects on insulin resistance and fatty acid metabolism.

Product Name:Mouse TNF-alpha/TNFA Recombinant Protein ((RPES3592)
Product Code:RPES3592
Size:10µg
Species:Mouse
Expressed Host:E.coli
Synonyms:Tumor Necrosis Factor, Cachectin, TNF-Alpha, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF-a, Tumor Necrosis Factor, Membrane Form, Tumor Necrosis Factor, Tnf,Tnfsf2,DIF,TNF-alpha,Tnfa,TNFalpha,Tnfsf1a,TNFSF2
Accession:P06804
Sequence: Asp89-Leu235
Activity:Measured in a cytotoxicity assay using L?929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 2-8 pg/ml.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse Tumor Necrosis Factor alpha is produced by our E.coli expression system and the target gene encoding Asp89-Leu235 is expressed.
Purity:> 95 % as determined by SDS-PAGE
Mol Mass:16.4 kDa
AP Mol Mass:14 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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