null

Recombinant Mouse Thrombopoietin/THPO Protein (RPCB1698)

SKU:
RPCB1698
Size:
10µg
Tag:
C-6His
Reactivity:
Mouse
Expression Host:
HEK293 cells
€139

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Mouse Thrombopoietin/THPO Protein
SKU:RPCB1698
Size:10µg
Tag:C-6His
Reactivity:Mouse
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Mouse Thrombopoietin/THPO Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:<0.1EU/μg
Purity:> 95% by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Gene ID:21832

Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. Thrombopoietin protein stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. Thrombopoietin protein is involved in cardiovascular disease as it regulates megakaryocyte development and enhances platelet adhesion/aggregation. It has been identified that surface c-MPL, the receptor for thrombopoietin protein, binds to the ligand and mediates the action.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:P40226-1
Product ImageRecombinant Mouse Thrombopoietin/THPO Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 60-80 kDa.
Product ImageRecombinant Mouse THPO stimulates cell proliferation of the MO7e human megakaryocytic leukemic cells. The EDâ‚…â‚€ for this effect is 0.45-1.80 ng/mL.

Related Products