Recombinant Mouse TGF-alpha Protein (RPCB1226)
- SKU:
- RPCB1226
- Size:
- 10µg
- Tag:
- C-hFc
- Reactivity:
- Mouse
- Expression Host:
- HEK293 cells
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Description
| Product Name: | Recombinant Mouse TGF-alpha Protein |
| SKU: | RPCB1226 |
| Size: | 10µg |
| Tag: | C-hFc |
| Reactivity: | Mouse |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Mouse TGF-alpha Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | <0.1EU/μg of the protein by LAL method. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Gene ID: | 21802 |
Transforming growth factor alpha (TGF-α) is a protein that in humans is encoded by the TGFA gene. TGF-alpha is a member of the EGF family of cytokines that are synthesized as transmembrane precursors and are characterized by the presence of one or several EGF structural units in their extracellular domain. Expression of TGF-alpha is widespread in tumors and transformed cells. TGF-alpha is also expressed in normal tissues during embryogenesis and in adult tissues, including pituitary, brain, keratinocytes, and macrophages.TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | P48030 |
 | Recombinant Mouse TGF- alpha/TGFA Protein was determined by SDS-PAGE with Coomassie Blue, showing bands at 32-35,40 kDa. |
 | Recombinant Mouse TGF- alpha/TGFA stimulates cell proliferation assay using Balb3T3 mouse fibroblast cells. The ED₅₀ for this effect is 0.43-1.72 ng/mL, corresponding to a specific activity of 15.81×105~2.33×106 units/mg. |
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