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Recombinant Mouse Sclerostin/SOST Protein (RPCB1809)

SKU:
RPCB1809
Size:
10µg
Tag:
C-His
Reactivity:
Mouse
Expression Host:
HEK293 cells
$251

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Mouse Sclerostin/SOST Protein
SKU:RPCB1809
Size:10µg
Tag:C-His
Reactivity:Mouse
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Mouse Sclerostin/SOST Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:<0.1EU/μg
Purity:> 95% as determined by by reducing SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Gene ID:74499

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:Q99P68
Product ImageRecombinant Mouse Sclerostin/SOST Protein was determined by SDS- PAGE with Coomassie Blue, showing a band at 30-45kDa.

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