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Recombinant Mouse Progranulin/PGRN/GRN Protein (RPCB1838)

SKU:
RPCB1838
Size:
100µg
Tag:
C-His
Reactivity:
Mouse
Expression Host:
HEK293 cells
€569

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Mouse Progranulin/PGRN/GRN Protein
SKU:RPCB1838
Size:100µg
Tag:C-His
Reactivity:Mouse
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Mouse Progranulin/PGRN/GRN Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:<1EU/μg
Purity:> 95% as determined by HPLC
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Gene ID:14824

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:P28798
Product ImageRecombinant Mouse Progranulin/PGRN/GRN Protein was determined by SDS-PAGE with Coomassie Blue, showing bands at 70-80 kDa.
Product ImageThe purity of Mouse Progranulin/PGRN/GRN is greater than 95% as determined by SEC- HPLC.

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