Recombinant Mouse Pleiotrophin/PTN Protein (RPCB0758)
- SKU:
- RPCB0758
- Size:
- 10µg
- Tag:
- C-6×His
- Reactivity:
- Mouse
- Expression Host:
- HEK293 cells
Frequently bought together:
Description
Product Name: | Recombinant Mouse Pleiotrophin/PTN Protein |
SKU: | RPCB0758 |
Size: | 10µg |
Tag: | C-6×His |
Reactivity: | Mouse |
Expression Host: | HEK293 cells |
Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Mouse Pleiotrophin/PTN Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
Endotoxin: | < 1 EU/μg of the protein by LAL method. |
Purity: | > 95% by SDS-PAGE. |
Formulation: | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation. |
Gene ID: | 19242 |
Pleiotrophin (PTN) is a secreted, strongly heparinbinding, developmentally regulated cytokine. PTN is a highlyconserved protein , Human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequenceidentity or greater. PTN and midkine share 50% amino acid (aa) sequence identity, share some functions, andconstitute a family. During development, PTN is involved in development of brain, bone, and organsundergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity,which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlatedwith neuronal development or stresses such as brain ischemia and Parkinson’s disease.
Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
Reconstitution: | Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. |
Swiss-Prot: | P63089 |