Recombinant Mouse LAIR-1/CD305 Protein (RPCB2096)
- SKU:
- RPCB2096
- Size:
- 100µg
- Tag:
- C-His
- Reactivity:
- Mouse
- Expression Host:
- HEK293 cells
Description
| Product Name: | Recombinant Mouse LAIR-1/CD305 Protein |
| SKU: | RPCB2096 |
| Size: | 100µg |
| Tag: | C-His |
| Reactivity: | Mouse |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Mouse LAIR-1/CD305 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | Less than 1EU per μg by the LAL method. |
| Purity: | > 95% as determined by Tris-Bis PAGE；> 95% as determined by HPLC |
| Gene ID: | 52855 |
LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | Q8BG84-1 |
 | Mouse LAIR1 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%. |
 | The purity of Mouse LAIR1 is greater than 95% as determined by SEC- HPLC. |
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