Mouse Kallikrein 1/KLK1 Recombinant Protein (RPES1284)
- SKU:
- RPES1284
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Frequently bought together:
Description
system_update_altDatasheet
Mouse Kallikrein 1/KLK1 Recombinant Protein
Kallikreins belongs to the family of trypsin-like serine proteases, many of which are associated with a variety of cancers. Kallikrein 1 (KLK1) is also known as tissue kallikrein and urinary kallikrein. KLK1 is synthesized as a 261 amino acid (aa) protein that contains a 18 aa signal peptide and a 241 aa proprotein. An important physiological function of KLK1 cleaves Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Kinins regulate vasodilation, blood pressure reduction, smooth muscle relaxation and contraction, pain induction and inflammation.
Product Name: | Mouse Kallikrein 1/KLK1 Recombinant Protein (RPES1284) |
Product Code: | RPES1284 |
Size: | 10µg |
Species: | Mouse |
Expressed Host: | Human Cells |
Synonyms: | Glandular kallikrein K1, KAL-B, Renal kallikrein, Tissue kallikrein-6, mGK-6 |
Accession: | P15947 |
Sequence: | Pro19-Asp261 |
Fusion tag: | C-His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Mouse Kallikrein-1 is produced by our Mammalian expression system and the target gene encoding Pro19-Asp261 is expressed with a 6His tag at the C-terminus. |
Purity: | > 95% as determined by reducing SDS-PAGE. |
Mol Mass: | 27.9 kDa |
AP Mol Mass: | 34-38 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM Tris,150mM NaCl,pH7.5. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |